Honoring a Legacy. Empowering a Future. Fighting Sickle Cell Disease.
Welcome to ENJAH-SCF
Honoring a Legacy. Empowering a Future. Fighting Sickle Cell Disease.
At The Elizabeth Nicole & Jacqueline Antoinette Holmes Sickle Cell Foundation (ENJAH-SCF), our mission is both deeply personal and profoundly impactful.
Founded in loving memory of twin sisters Elizabeth (“Lizzy”) Nicole and Jacqueline (“Jackie”) Antoinette Holmes—two courageous young women who bravely faced the challenges of sickle cell disease with extraordinary grace and strength—our foundation was born from love, grief, hope, and an unwavering determination to create lasting change.
We believe that every individual living with sickle cell disease (SCD) deserves not only access to quality medical care, but also compassion, dignity, and respect.. ENJAH-SCF strives to uplift, empower families, and bring hope where it’s needed most.
Who We Serve
Supporting Underserved Communities Affected by Sickle Cell
Sickle cell disease (SCD) is a class of rare genetic blood disorders that mainly impacts Black Americans but is also diagnosed in individuals of Hispanic, Mediterranean, Middle Eastern, and Indian ancestry. At ENJAH-SCF, we provide resources, advocacy, and support tailored to those disproportionately affected by this chronic and often misunderstood condition.
Bridging Gaps in Healthcare Access
We work to eliminate the disparities that limit access to quality care for sickle cell patients.
Raising Awareness Through Education
Our campaigns reduce stigma and spread knowledge in high-impact communities.
Standing With Families
We offer emotional, financial, and educational support for those impacted by SCD.
Who We Are
Founded in Love. Driven by Purpose.
The Elizabeth (“Lizzy”) Nicole and Jacqueline (“Jackie”) Antoinette Holmes Sickle Cell Foundation (ENJAH-SCF) was created to honor the lives and legacies of twin sisters who faced sickle cell disease with remarkable strength and grace.
Born from love and a determination to make a difference, ENJAH-SCF works to bring hope, awareness, and support to families affected by sickle cell disease. Through education, advocacy, and community programs, we strive to improve quality of life and advance health equity for all who live with this condition.
Why We Exist
Sickle cell disease disproportionately affects African, Hispanic, Middle Eastern, and Indian populations— communities that too often face pain, stigma, and limited access to quality care. The Elizabeth Nicole & Jacqueline Antoinette Holmes Sickle Cell Foundation (ENJAH-SCF) exists to confront these disparities through education, advocacy, and compassionate support. Our mission is to bring hope, dignity, and equity to every life touched by sickle cell disease.
Our Mission
At the Elizabeth (“Lizzy”) Nicole & Jacqueline (“Jackie”) Antoinette Holmes Sickle Cell Foundation (ENJAH-SCF), our mission is to empower, educate, and uplift individuals and families affected by sickle cell disease.
Through compassionate outreach, advocacy, and community programs, we strive to:
- Fund college scholarships and emergency financial relief for patients and families living with sickle cell disease.
- Expand lifesaving donor initiatives.
- Drive education, outreach, and public awareness to break the stigma.
- Build sustainable fundraising and partnerships, and
- Strengthen advocacy efforts for innovative treatment, policy change, and a cure.
Empowering the Sickle Cell Community Through Action
At ENJAH-SCF, we focus on advocacy, education, and support to change the narrative for individuals and families living with sickle cell disease. Our work is rooted in compassion— and powered by the enduring legacy of those we serve.
Creating Equity in Sickle Cell Care
Through advocacy, education, and direct support, ENJAH-SCF is committed to closing the gaps in treatment and awareness for underrepresented communities impacted by sickle cell disease.
What We Do
Delivering Support, Driving Change
At ENJAH-SCF, we combine compassion with action. From scholarships and emergency support to public awareness and advocacy, our programs are designed to meet the real needs of individuals and families affected by sickle cell disease.
Core Programs
- Family Support and Patient Assistance Program
- College Education and Scholarship Program
- Community Awareness and Outreach Program
- Advocacy and Policy Initiative
- Health Equity and Research Partnership Program
🎓 Scholarship Programs
We empower students researching and living with sickle cell disease by providing scholarships that support their academic and career goals, helping them overcome barriers to higher education.
💸 Emergency Financial Relief
We offer urgent financial support to families facing the economic burden of sickle cell complications—covering expenses like medical bills, transportation, and household needs.
📢 Awareness & Education
Our outreach campaigns educate communities about SCD, reduce stigma, and promote early diagnosis. We host workshops, share resources, and spread awareness through events and digital platforms.
🏛 Advocacy & Research Partnerships
ENJAH-SCF works alongside healthcare providers, researchers, and policymakers to advocate for improved care, increase funding, and advance life-saving treatment options.
In Memory, With Purpose
This foundation was created not only to fight for the future, but to honor the past. Lizzy and Jackie’s journey with SCD was filled with both hardship and resilience. By sharing their legacy, we’re turning pain into purpose—empowering others to live boldly and fully.
Make a Difference in the Lives of Those with Sickle Cell Disease
When you get involved with ENJAH-SCF, you become part of a powerful movement to improve the lives of individuals and families impacted by sickle cell disease. Your time, donation, or advocacy can spark real change.
Ways to Support:
- Donate to fund scholarships, outreach, and emergency assistance
- Volunteer your skills, time, or leadership at community events
- Host or join a fundraiser to raise awareness and resources
Support With Purpose
Why Your Support Matters
Sickle cell disease remains underfunded and underserved. By supporting ENJAH-SCF, you help break barriers in care, education, and advocacy. Every contribution helps us reach more lives with dignity and hope.
- Together, we can build a future where no one faces sickle cell disease alone.
- With your help, we turn compassion into action.
- Let’s create lasting impact—one donation, one volunteer, one voice at a time.
Volunteer to Uplift Lives
Whether it’s one hour or one event, your time can make a lasting impact.
Fundraise for a Cause That Matters
Start a campaign, organize a local event, or share your story to help raise awareness.
Why Our Work Matters
Bridging the Gaps in Sickle Cell Awareness and Care
Despite being one of the most common genetic blood disorders, sickle cell disease remains drastically underfunded and often misunderstood. At ENJAH-SCF, we work to bring visibility, support, and systemic change to communities most affected by this condition.
Our Goals:
- Sickle cell disease doesn’t wait—neither do we.
- Through every program, partnership, and donation, we are rewriting the future.
- This is more than a cause—it’s a call to action.
- Together, we are building hope where it’s needed most.
Fundraise for Sickle Cell Awareness
Turn Your Ideas Into Impact
You don’t need a large organization to make a difference—just a big heart and the willingness to act. Whether it’s a birthday fundraiser, charity run, or school event, your effort directly supports programs that change lives for those living with sickle cell disease.
Creative Ways to Get Involved
From bake sales to virtual events, every fundraiser brings more awareness and support to underserved communities. We'll equip you with the tools and guidance to make your campaign a success.
Empower Your Community Through Action
Fundraising isn’t just about raising money—it’s about raising voices. When you host a campaign, you educate others, share real stories, and fuel hope for patients and families affected by sickle cell disease.
Volunteer With Us
Join the Fight to Uplift Lives Affected by Sickle Cell Disease
Volunteering with ENJAH-SCF means becoming part of a passionate team dedicated to driving awareness, building stronger communities, and offering real support to families facing the daily challenges of sickle cell disease. No matter your background or skill set, your time can make a lasting impact.
Event Planning & Support
Help us organize and run community events, fundraisers, and educational programs.
Mentorship & Advocacy
Support young people living with SCD and advocate for better care in your community.
Stay Connected
Sign up for our newsletter to get updates about sickle cell education, upcoming events, scholarship opportunities, and ways to make an impact.
In Loving Memory of Lizzy & Jackie Holmes
A Legacy of Strength, Love, and Courage
Elizabeth (“Lizzy”) and Jacqueline (“Jackie”) Holmes were twin sisters whose lives, though far too short, left a permanent mark on the world. Their journey with sickle cell disease shaped the mission of ENJAH-SCF—to bring hope, healing, and dignity to others walking a similar path.
Their Impact Lives On:
- Lizzy passed away at age 8, but her bravery continues to inspire our youth programs
- Jackie fought until 32, and her strength fuels our advocacy work
- Together, their lives symbolize the importance of awareness, support, and family
A Tribute That Inspires Action
Their memory lives through every donation, scholarship, and community event hosted by ENJAH-SCF.
Honoring Them Through Service
We turn their story into support—serving others with the same love they gave to the world.
Light a Candle, Share a Memory
Celebrate Lizzy and Jackie’s legacy by leaving a tribute, sharing a story, or giving in their honor.
