Honoring a Legacy. Empowering a Future. Fighting Sickle Cell Disease.
At The Elizabeth Nicole & Jacqueline Antoinette Holmes Sickle Cell Foundation (ENJAH-SCF), our mission is both deeply personal and profoundly impactful. Founded in loving memory of twin sisters Elizabeth (“Lizzy”) Nicole and Jacqueline (“Jackie”) Antoinette Holmes—two courageous young women who bravely faced the challenges of sickle cell disease with extraordinary grace and strength—our foundation was born from love, grief, hope, and an unwavering determination to create lasting change. We believe that every individual living with sickle cell disease (SCD) deserves not only access to quality medical care, but also compassion, dignity, and respect.. ENJAH-SCF strives to uplift, empower families, and bring hope where it’s needed most.
The Elizabeth Nicole & Jacqueline Antoinette Holmes Sickle Cell Foundation (ENJAH-SCF) is a 501(c)(3) nonprofit organization dedicated to improving the lives of individuals and families affected by sickle cell disease (SCD). Founded in memory of twin sisters Elizabeth (“Lizzy”) Nicole Holmes and Jacqueline (“Jackie”) Antoinette Holmes, ENJAH-SCF was established to honor their lives by transforming personal loss into lasting hope for others.
Inspired by Lizzy and Jackie’s courage, resilience, and unwavering spirit, our organization works to expand education and public awareness, strengthen support systems, advance research, promote health equity, and build partnerships that improve opportunities and quality of life for individuals and families living with sickle cell disease.
Sickle cell disease is one of the most common inherited blood disorders in the United States, yet it remains one of the most underfunded and misunderstood chronic health conditions. Many individuals and families face lifelong medical challenges, healthcare disparities, financial burdens, and barriers to quality care.
ENJAH-SCF exists to help address these challenges by expanding education, advancing research, promoting health equity, supporting individuals and families, and building partnerships that improve access to care, resources, and opportunities for people impacted by sickle cell disease.
To uplift individuals and families affected by sickle cell disease through advocacy, education, financial assistance, research, and community engagement.
To create a future where every individual affected by sickle cell disease has equitable access to quality healthcare, innovative treatment options, and unwavering community support, leading to improved quality of life and, ultimately, a cure for future generations.
ENJAH-SCF serves individuals, families, professionals, and organizations dedicated to improving the lives of people impacted by sickle cell disease, including:
Dedicated leadership committed to advancing health equity, stengthening communities, and improving the lives of individuals and families affected by sickle cell disease.
Dr. Peggy Ann Russ-Williams is the co-founder and Executive Director of The Elizabeth Nicole & Jacqueline Antoinette Holmes Sickle Cell Foundation (ENJAH-SCF). She was motivated by the lives and legacies of her second cousins, twin sisters Elizabeth (“Lizzy”) Nicole Holmes and Jacqueline (“Jackie”) Antoinette Holmes. Dr. Russ-Williams helped establish ENJAH-SCF to honor their memory and address the ongoing challenges faced by individuals and families living with sickle cell disease.
Dr. Russ-Williams holds a Doctor of Business Administration (DBA) in Healthcare Management, a Master of Business Administration (MBA) in Healthcare Management, and a Master of Public Administration (MPA) in Public Finance and Management. She has many years of experience in nonprofit leadership, healthcare administration, strategic planning, financial management, grant development and compliance, organizational governance, and research.
In her capacity as Executive Director and Grants & Compliance Officer, Dr. Russ-Williams gives strategic leadership to ENJAH-SCF, taking responsibility for the day-to-day operations of the organization, the development of its programs, grant strategy, compliance, community partnerships, and its long-term growth. She is committed to promoting health equity, extending educational opportunities, supporting research, and improving the systems of care for individuals and families affected by sickle cell disease.
Our aim is to create a future in which all those affected by sickle cell disease are able to obtain quality healthcare, have access to new treatments, and benefit from strong community support. We hope that this will enhance people’s lives and, some day, result in a cure for future generations.
This foundation was created not only to fight for the future, but to honor the past. Lizzy and Jackie’s journey with SCD was filled with both hardship and resilience. By sharing their legacy, we’re turning pain into purpose—empowering others to live boldly and fully.
Elizabeth (“Lizzy”) and Jacqueline (“Jackie”) Holmes were twin sisters whose lives, though far too short, left a permanent mark on the world. Their journey with sickle cell disease shaped the mission of ENJAH-SCF—to bring hope, healing, and dignity to others walking a similar path.
Their Impact Lives On:
Their memory lives through every donation, scholarship, and community event hosted by ENJAH-SCF.
We turn their story into support—serving others with the same love they gave to the world.
Celebrate Lizzy and Jackie’s legacy by leaving a tribute, sharing a story, or giving in their honor.
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