Honoring a Legacy. Empowering a Future. Fighting Sickle Cell Disease.

Who We Are

The Elizabeth Nicole & Jacqueline Antoinette Holmes Sickle Cell Foundation (ENJAH-SCF) is a nonprofit organization committed to improving the lives of individuals and families impacted by sickle cell disease (SCD). Inspired by the courageous lives of twin sisters Lizzy and Jackie Holmes, ENJAH-SCF was created to turn loss into legacy—and compassion into community care.

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Legacy in Action

ENJAH-SCF was built to ensure that Lizzy and Jackie’s light continues to shine by empowering others every day.

We honor their legacy by:

Empowering Lives, Honoring Legacy

A Mission Rooted in Love, Focused on Impact

At ENJAH-SCF, we transform pain into purpose. Founded in memory of Lizzy and Jackie Holmes, our work is dedicated to changing the future of sickle cell disease through advocacy, education, and compassionate care.

We don’t just raise awareness—we raise hope.
We don’t just offer support—we offer strength.
ENJAH-SCF stands as a living tribute to two courageous women and a beacon for all who walk the path of sickle cell disease.

Community-First Approach

Everything we do is guided by the needs, stories, and strength of the sickle cell community.

Results That Matter

From scholarships to support services, we focus on real outcomes that uplift real people.

Why We Exist

Sickle cell disease disproportionately affects African, Hispanic, Middle Eastern, and Indian communities. Yet despite its prevalence, it remains one of the most underfunded and misunderstood health conditions. Many patients face lifelong pain, limited treatment access, and stigma. ENJAH-SCF is here to change that.

We exist to bring awareness, offer relief, and push for change—so no one has to fight sickle cell alone.

Our Mission

To uplift individuals and families affected by sickle cell disease through advocacy, education, financial assistance, and community engagement, with a vision for a future where SCD is not a barrier—but a battle that can be won.

Equity in Action

Closing the Gaps in Sickle Cell Support

ENJAH-SCF is committed to health equity for underserved communities affected by sickle cell disease. Through culturally informed advocacy, direct assistance, and inclusive education, we ensure every voice is heard and every need is addressed with dignity and compassion.

Every Voice Matters

We advocate for equal care, one conversation at a time.

Core Programs

Turning Purpose Into Action

ENJAH-SCF transforms its mission into real-world impact through accessible, high-impact programs that support, educate, and empower individuals and families affected by sickle cell disease.

Empowering Education

Scholarships for students with SCD, helping them reach academic and career goals.

Emergency Family Support

Direct aid for families during health-related financial crises.

Raising Awareness Nationwide

Educational campaigns that reduce stigma and increase early diagnosis.

Join Our Mission

Together, We Create Change That Lasts

ENJAH-SCF isn’t just an organization—it’s a movement driven by love, resilience, and the unwavering belief that no one should face sickle cell disease alone. Your involvement—no matter how big or small—can ignite hope, restore dignity, and change lives for generations to come.

Ways You Can Make an Impact

Becoming part of the ENJAH-SCF community means using your voice, resources, and heart to uplift others.

Here’s how you can help:

Make a Life-Changing Impact Today